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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
10.3
Human Site:
T533
Identified Species:
17.44
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
T533
P
C
L
T
Q
L
L
T
A
A
K
P
E
Q
A
Chimpanzee
Pan troglodytes
XP_509441
819
90122
T503
R
E
G
M
L
A
S
T
V
S
Q
S
N
V
V
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
A96
L
F
E
C
L
S
L
A
Y
S
G
K
L
V
S
Dog
Lupus familis
XP_546925
857
93734
T538
P
C
L
T
Q
L
L
T
A
A
K
P
E
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
A545
L
T
Q
L
L
R
A
A
K
P
E
Q
A
L
E
Rat
Rattus norvegicus
Q6AXT8
471
49872
E177
L
M
A
A
E
P
Y
E
T
I
A
F
K
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
D577
A
K
Q
E
P
A
F
D
A
P
H
V
H
S
P
Frog
Xenopus laevis
NP_001084764
548
60887
S254
E
I
S
D
T
L
F
S
T
I
Y
S
H
Q
H
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
P508
I
V
P
A
N
P
L
P
S
P
Q
L
I
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
T512
T
S
N
S
R
L
Q
T
A
V
A
N
S
S
S
Honey Bee
Apis mellifera
XP_394429
1014
115124
Y694
N
Q
T
T
T
M
K
Y
I
S
S
M
L
P
P
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
G595
P
G
G
F
K
M
S
G
T
T
S
G
V
P
T
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
A995
A
L
L
T
Q
L
L
A
E
G
A
G
K
Y
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
T765
P
A
P
P
R
L
P
T
H
S
A
S
P
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
6.6
93.3
N.A.
0
0
N.A.
N.A.
6.6
13.3
6.6
N.A.
20
6.6
6.6
33.3
P-Site Similarity:
100
20
20
93.3
N.A.
6.6
13.3
N.A.
N.A.
6.6
20
20
N.A.
40
20
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
15
0
15
8
22
29
15
29
0
8
0
8
% A
% Cys:
0
15
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% D
% Glu:
8
8
8
8
8
0
0
8
8
0
8
0
15
0
8
% E
% Phe:
0
8
0
8
0
0
15
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
15
0
0
0
0
8
0
8
8
15
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
8
0
15
0
8
% H
% Ile:
8
8
0
0
0
0
0
0
8
15
0
0
8
0
0
% I
% Lys:
0
8
0
0
8
0
8
0
8
0
15
8
15
0
0
% K
% Leu:
22
8
22
8
22
43
36
0
0
0
0
8
15
15
0
% L
% Met:
0
8
0
8
0
15
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
29
0
15
8
8
15
8
8
0
22
0
15
8
22
29
% P
% Gln:
0
8
15
0
22
0
8
0
0
0
15
8
0
22
0
% Q
% Arg:
8
0
0
0
15
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
8
0
8
15
8
8
29
15
22
8
15
15
% S
% Thr:
8
8
8
29
15
0
0
36
22
8
0
0
0
0
22
% T
% Val:
0
8
0
0
0
0
0
0
8
8
0
8
8
22
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
8
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _